2025 MLB All-Star Game Odds, Predictions, Home Derby Picks

American League Lineup and Analysis

Manager

Starters

• • C – Cal Raleigh, Seattle Mariners
  • 1B – Vladimir Guerrero Jr., Toronto Blue Jays
  • 2B – Gleyber Torres, Detroit Tigers
  • 3B – Junior Caminero, Tampa Bay Rays
  • SS – Jacob Wilson, Athletics
  • OF – Aaron Judge, New York Yankees
  • OF – Riley Greene, Detroit Tigers
  • OF – Javier Baez, Detroit Tigers
  • DH – Ryan O’Hearn, Baltimore Orioles
  • SP – Tarik Skubal, Detroit Tigers

Reserves

• • C – Alejandro Kirk, Toronto Blue Jays
  • INF – Jonathan Aranda, Tampa Bay Rays
  • INF – Alex Bregman, Boston Red Sox
  • INF – Jazz Chisholm Jr., New York Yankees
  • INF – Maikel Garcia, Kansas City Royals
  • INF – Brandon Lowe, Tampa Bay Rays
  • INF – Zach McKinstry, Detroit Tigers
  • INF – Isaac Paredes, Houston Astros
  • INF – Jeremy Pena, Houston Astros
  • INF – Bobby Witt Jr., Kansas City Royals
  • OF – Randy Arozarena, Seattle Mariners
  • OF – Byron Buxton, Minnesota Twins
  • OF – Steven Kwan, Cleveland Guardians
  • OF – Julio Rodriguez, Seattle Mariners
  • DH – Brent Rooker, Athletics

Pitchers

• • SP – Hunter Brown, Houston Astros
  • SP – Kris Bubic, Kansas City Royals
  • SP – Garrett Crochet, Boston Red Sox
  • SP – Jacob deGrom, Texas Rangers
  • SP – Max Fried, New York Yankees
  • SP – Yusei Kikuchi, LA Angels
  • SP – Casey Mize, Detroit Tigers
  • SP – Drew Rasmussen, Tampa Bay Rays
  • SP – Carlos Rodon, New York Yankees
  • SP – Joe Ryan, Minnesota Twins
  • SP – Shane Smith, Chicago White Sox
  • SP – Bryan Woo, Seattle Mariners
  • RP – Aroldis Chapman, Boston Red Sox
  • RP – Carlos Estevez, Kansas City Royals
  • RP – Josh Hader, Houston Astros
  • RP – Andres Munoz, Seattle Mariners

If you’re a fan of the Detroit Tigers, you are going to like what you see from the American League roster! The Tigers have three hitters in the starting lineup, an additional one coming off the bench, and two starting pitchers.

Two starting outfielders are Tigers, as Riley Greene and Javier Baez will be out there with AL MVP favorite Aaron Judge. It’s been an incredible rise to prominence for Baez after he struggled to find traction in his first four years in Detroit.

Aaron Judge absolutely OBLITERATED Mark McGwire’s record to become the fastest ever to 350 career home runs 🤯 pic.twitter.com/m0yc7HalCX

— The Yankee Report (@YankeeReport_) July 13, 2025

With Judge and Cal Raleigh on the same team, the American League has the two top sluggers in baseball. Raleigh leads MLB with 38 home runs, while Judge follows in second with 35. However, the next player in the American League is Riley Greene in eighth with 24 long balls.

Raleigh, Judge, and Greene are first, second, and third in RBIs in the Major Leagues. There is enough firepower on the American League to deliver plenty of damage. Overall, the American League holds a total team bWAR of 44.3 for position players.

Meanwhile, the pitching staff has five hurlers who have been involved in the Cy Young race, including the clear favorite, Tarik Skubal. Skubal is well ahead of the group, as he posted a 2.23 ERA and 0.83 WHIP in the first half. Max Fried, Kris Bubic, Hunter Brown, and Garrett Crochet, along with Skubal, are a potent lineup.

As a combined unit, the American League has a cumulative ERA of 2.34.

National League Lineup and Analysis

Manager

• • Dave Roberts, Los Angeles Dodgers

Starters

• • C – Will Smith, Los Angeles Dodgers
  • 1B – Freddie Freeman, Los Angeles Dodgers
  • 2B – Ketel Marte, Arizona Diamondbacks
  • 3B – Manny Machado, San Diego Padres
  • SS – Francisco Lindor, New York Mets
  • OF – Ronald Acuna Jr., Atlanta Braves
  • OF – Pete Crow-Armstrong, Chicago Cubs
  • OF – Kyle Tucker, Chicago Cubs
  • DH – Shohei Ohtani, Los Angeles Dodgers
  • SP – Paul Skenes, Pittsburgh Pirates

Reserves

• • C – Hunter Goodman, Colorado Rockies
  • INF – Pete Alonso, New York Mets
  • INF – Elly De La Cruz, Cincinnati Reds
  • INF – Brendan Donovan, St. Louis Cardinals
  • INF – Matt Olson, Atlanta Braves
  • INF – Eugenio Suarez, Arizona Diamondbacks
  • OF – Corbin Carroll, Arizona Diamondbacks
  • OF – Kyle Stowers, Miami Marlins
  • OF – Fernando Tatis Jr., San Diego Padres
  • OF – James Wood, Washington Nationals
  • DH – Kyle Schwarber, Philadelphia Phillies

Pitchers

• • SP – Andrew Abbott, Cincinnati Reds
  • SP – Matthew Boyd, Chicago Cubs
  • SP – Mackenzie Gore, Washington Nationals
  • SP – Clayton Kershaw, Los Angeles Dodgers
  • SP – Jacob Misiorowski, Milwaukee Brewers
  • SP – Freddy Peralta, Milwaukee Brewers
  • SP – David Peterson, New York Mets
  • SP – Robbie Ray, San Francisco Giants
  • SP – Chris Sale, Atlanta Braves
  • SP – Logan Webb, San Francisco Giants
  • SP – Zack Wheeler, Philadelphia Phillies
  • SP – Yoshinobu Yamamoto, Los Angeles Dodgers

The National League starting lineup features some heavyweights. Shohei Ohtani won’t pitch in the All-Star Game, but he will suit up as a DH. Ohtani hit .276 with 32 home runs and 60 RBIs in the first half. Despite being off the pace of last year’s record-breaking numbers, Ohtani is on course to win the NL MVP for the second straight season. It would also be his third consecutive MVP, and fourth award of his career, after winning two with the Los Angeles Angels in 2021 and 2023.

Shohei Ohtani’s NL ranks this season:

1st in HR: 32
1st in SLG:.608
1st in OPS: .988
3rd in triples: 7
4th in BB: 60 pic.twitter.com/uNwE54EcuP

— MLB (@MLB) July 13, 2025

He and Ronald Acuna Jr. should be a load to handle for American League pitching. Acuna Jr. has been red-hot in the batter’s box since returning on May 23. The 27-year-old from La Guaira, Venezuela, is hitting .325 with 12 home runs and 22 RBIs. Acuna Jr. and Ohtani should shine, but I suspect Cubs’ standout 23-year-old center fielder Pete Crow-Armstrong could steal the show.

Armstrong notched a .265 batting average with 25 home runs and 71 RBIs in the first half. He joins Kyle Tucker as one of two Cubs in the starting lineup for the National League.

While the American League has the top two home run hitters in baseball, the National League has four hitters ranked from third to sixth on their roster. The reserves on the National League roster are mightily impressive.

Having the luxury of Kyle Schwarber, Pete Alonso, James Wood, Eugenio Suarez, Elly De La Cruz, Corbin Carroll, among others, off the bench is incredible. Suarez and Schwarber could easily be starters, with Suarez as one of the hottest hitters in baseball at the moment. He’s belted 10 long balls since June 19, and 31 overall in 2025!

30 home runs for Eugenio Suárez! pic.twitter.com/o1mtcYn3Ts

— MLB (@MLB) July 13, 2025

The rotation features some lockdown arms this year. NL Cy Young favorite Paul Skenes gets the call as the All-Star starter in only his second season in the Major Leagues. Skenes is the clear frontrunner for the Cy Young, as he carries a 2.01 ERA and 0.93 WHIP in the second half.

Zack Wheeler, Chris Sale, and Yoshinobu Yamamoto provide the National League with strong options behind Skenes. Paired with a well-balanced offense, the National League will be tough!